Aims & Scope
Otolaryngology Advances publishes original research on the biomechanical, physiological, and technological foundations of ear, nose, throat, and head-neck systems, emphasizing device innovation, tissue engineering, and non-clinical scientific investigation.
Core Research Domains
Auditory System Biomechanics
- Cochlear mechanics and fluid dynamics
- Ossicular chain biomechanics and vibration analysis
- Tympanic membrane material properties and modeling
- Vestibular system mechanics and balance physiology
- Cochlear implant electrode design and biocompatibility
- Acoustic signal processing in biological systems
"Finite element analysis of ossicular chain mechanics under varying pressure conditions" or "Novel biocompatible materials for cochlear implant electrodes with enhanced neural interface properties"
Respiratory Tract Engineering
- Nasal airflow dynamics and computational fluid modeling
- Sinus cavity biomechanics and pressure distribution
- Laryngeal tissue biomechanics and vocal fold vibration
- Airway scaffold design and tissue engineering
- Mucociliary clearance mechanisms and modeling
- Biomaterial development for airway reconstruction
"Computational fluid dynamics analysis of nasal airflow patterns in reconstructed nasal cavities" or "Development of bioengineered tracheal scaffolds using decellularized matrices"
Head-Neck Biomaterials & Devices
- Craniofacial implant materials and osseointegration
- Thyroid tissue engineering and biomimetic scaffolds
- Salivary gland regeneration and bioengineering
- Facial nerve regeneration biomaterials
- Drug delivery systems for head-neck applications
- Biocompatibility testing of ENT devices
"Mechanical characterization of novel titanium alloys for craniofacial reconstruction" or "Bioengineered salivary gland organoids for functional tissue replacement"
Physiological Sensing & Monitoring
- Biosensor development for ENT applications
- Wearable devices for respiratory monitoring
- Acoustic analysis systems and signal processing
- Sleep-disordered breathing detection technologies
- Pressure and flow measurement instrumentation
- Non-invasive diagnostic device engineering
"Development of miniaturized pressure sensors for real-time sinus cavity monitoring" or "Machine learning algorithms for acoustic analysis of vocal fold vibration patterns"
Secondary Focus Areas
Cross-Disciplinary Biomechanics
- Neuromechanics of cranial nerve function
- Biomechanical modeling of pediatric airway development
- Age-related changes in tissue mechanical properties
- Comparative biomechanics across species
Advanced Materials Science
- Nanomaterials for ENT device coatings
- Smart materials with responsive properties
- Biodegradable polymers for temporary implants
- Surface modification techniques for biocompatibility
Computational Modeling
- Finite element analysis of anatomical structures
- Multi-scale modeling of physiological systems
- Machine learning for biomechanical prediction
- Virtual prototyping of medical devices
Regenerative Technologies
- Stem cell scaffolds for tissue regeneration
- Bioreactor design for tissue culture
- Growth factor delivery systems
- 3D bioprinting of ENT tissues
Instrumentation Development
- Robotic systems for precision manipulation
- Imaging device engineering and optimization
- Microfluidic systems for diagnostic applications
- Haptic feedback systems for training
Biomolecular Engineering
- Protein engineering for tissue scaffolds
- Genetic factors in tissue mechanical properties
- Molecular mechanisms of osseointegration
- Biomarker discovery for device monitoring
Emerging Research Frontiers
Article Types & Editorial Priorities
Fast-Track Review
Standard Review
Exceptional Circumstances Only
Editorial Standards & Requirements
Reporting Guidelines
All submissions must follow discipline-appropriate reporting standards: ARRIVE for animal studies, CONSORT for device trials, PRISMA for systematic reviews, and STROBE for observational research.
Data Availability
Raw data, computational models, and device specifications must be made available in public repositories or as supplementary materials. Proprietary restrictions must be disclosed.
Ethics Compliance
Research involving human subjects or animal models requires institutional review board approval. Cadaveric studies must include appropriate consent documentation.
Preprint Policy
Preprint deposition is encouraged. Manuscripts posted on recognized preprint servers remain eligible for consideration. Authors must disclose preprint DOI at submission.
Reproducibility
Detailed methodology, material specifications, and computational code must enable independent replication. Device designs should include CAD files when feasible.
Conflict of Interest
All financial relationships, patent applications, and commercial interests related to submitted work must be disclosed. Industry collaborations require transparency statements.
