Instructions for Authors

Comprehensive guidelines for preparing and submitting stem cell research manuscripts to the journal.

ESCR publishes several article formats, each with specific requirements tailored to its purpose and expected contribution to regenerative medicine knowledge.

Organize original stem cell research manuscripts following standard scientific format. Clear structure enhances readability and facilitates peer review of regenerative medicine articles.

• Title page: Concise title (maximum 150 characters), all author names and affiliations, corresponding author contact, word count, and conflict disclosures
• Abstract: Structured format with background, methods, results, and conclusions. Include 4-6 keywords for indexing
• Introduction: Background context, research question rationale, and study objectives for stem cell investigation
• Methods: Detailed methodology enabling replication, including cell sources, culture conditions, and analysis approaches
• Results: Objective findings without interpretation, organized logically with supporting tables and figures
• Discussion: Interpretation of findings, comparison with existing literature, limitations, and therapeutic implications
• References: Vancouver format throughout manuscript with proper citation

Proper formatting ensures consistent presentation and efficient processing of stem cell manuscripts through the production workflow.

All stem cell research must comply with established ethical standards. Authors bear responsibility for ensuring appropriate approvals and consent for cellular research.

• Institutional Review Board or Ethics Committee approval required for research involving human materials
• Informed consent documentation for patient-derived samples and iPSC generation
• ISSCR guidelines compliance for human embryonic stem cell research
• Complete conflict of interest disclosure including industry relationships
• Cell line authentication and mycoplasma testing confirmation

ESCR recommends adherence to appropriate reporting guidelines based on study design. These standards ensure completeness and transparency in stem cell research reporting.

• ARRIVE: Animal studies involving stem cell transplantation or in vivo models
• CONSORT: Randomized clinical trials evaluating stem cell interventions
• PRISMA: Systematic reviews and meta-analyses of regenerative medicine literature
• MIAME: Microarray and gene expression studies from stem cell experiments
• MIQE: Quantitative PCR experiments for gene expression analysis

Submit manuscripts through our online ManuscriptZone system. The platform guides authors through required information and document uploads for stem cell submissions.

All stem cell submissions undergo rigorous peer review by at least two qualified reviewers with relevant expertise in regenerative medicine. The review process evaluates scientific validity, methodological rigor, originality, and significance. Authors receive detailed feedback with constructive suggestions. Initial editorial decisions are typically communicated within four weeks of submission.

ESCR uses Vancouver reference style throughout all manuscripts. References should be numbered consecutively in order of first citation using superscript numerals. Include up to six authors; if more than six, list first six followed by "et al." Ensure all references are complete with author names, article titles, journal abbreviations, publication year, volume, and page numbers. Reference accuracy is the author's responsibility and incomplete references may delay manuscript processing.

All listed authors must meet ICMJE authorship criteria demonstrating substantial contributions. Each author should have participated in conception or design, data acquisition or analysis, manuscript drafting or critical revision, and final approval. Authors must agree to be accountable for all aspects of the work. Acknowledge individuals who contributed but do not meet full authorship criteria in a separate acknowledgments section.

Manuscripts must be submitted in English with clear, concise scientific writing. Authors whose first language is not English are encouraged to seek professional language editing before submission to ensure clarity. ESCR offers language editing services through our Language Editing Service page for authors needing assistance with English presentation.

ESCR strongly encourages data sharing to support reproducibility and transparency in stem cell research. Sequencing data should be deposited in NCBI GEO or similar databases before publication. Novel cell lines should be made available to qualified researchers whenever possible through established cell repositories to accelerate scientific progress in regenerative medicine.

When revision is requested, address all reviewer comments systematically with point-by-point responses. Highlight changes using track changes or colored text. Revisions are typically due within 30 days for minor and 60 days for major revisions. Extensions may be requested by contacting the editorial office if additional time is needed for complex experimental revisions.

All accepted articles are published under Creative Commons Attribution 4.0 International License (CC BY 4.0), enabling broad sharing and reuse. Authors retain copyright. Article processing charges apply upon acceptance; fee waivers available for qualifying authors from low-income countries or experiencing financial hardship.

ESCR provides ongoing support after publication. Published authors can request citation metrics, altmetric data, and usage statistics for their stem cell research. The editorial team assists with corrections, author profile updates, and repository integration for long-term accessibility of your regenerative medicine discoveries.