Journal of Systems Biology

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Systems Biology-Cancer biology; hormonal signals; drug discovery -Michael Lu

United States

Florida Atlantic University

(561) 297-0892, 561-297-4828

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Michael Lu

Address:

Charles E. Schmidt College of Medicine
Florida Atlantic University
777 Glades Road
Boca Raton, FL 33431

Research Interests:

Cancer biology; hormonal signals; drug discovery

Biography:

Publications:

  1. Jean-Philippe, J., Paz, S., Lu, M.L., Caputi, M. (2014). A truncated hnRNP A1 isoform, lacking the RGG-box RNA binding domain, can efficiently regulate HIV-1 splicing and replication. Biochim Biophys Acta, 1839(4), 251-8.
  2. Wang H, McNight NC, Zhang T, Lu ML, Balk SP and Yuan X SOX9 is Expressed in normal prostate basal cells and regulates androgen receptor expression in prostate cancer cells. Cancer Res. 2007; In Press
  3. Yuan X, Li T, Wang H, Zhang T, Barua M, Borgesi RA, Buble GJ, Lu ML and Balk SP Androgen receptor remains critical for cell cycle progression in androgen independent CWR22 prostate cancer cells. Am. J. Path. 2006; 169: 682-696
  4. Jia Z, Zhang A, Barbier L, Vadnais J, Noel J, Lu ML and. Nabi IR. Autocrine c- Met/HGF-R activation of localized Rho/ROCK/p38 MAP kinase signaling directs the protrusion of tumour cell pseudopodia. Biol. Cell 2006; 96:337-351
  5. Freeman MR, Cinar B and Lu ML. Membrane rafts as potential sites of nongenomic hormonal signaling in prostate cancer. Trens Endocrin. Metabol. 2005, 16:273-279
  6. Kaur R, Liu X, Gjoerup O, Zhang A, Balk SP, Yuan X, Schneider MC and Lu ML. Activation of p21 Activated Kinase (PAK6) by MAP kinase kinase 6 and p38 MAP kinase. J. Biol. Chem. 2005; 280:3323-3330.
  7. Mukhopadhyay NK, Gilchrist D, Gordon GJ, Chen C-J, Bueno R, Lu ML, Salgia R, Sugarbaker DJ, Jaklitsh MT. Integrin Dependent Protein Tyrosine Phosphorylation is a Key Regulatory Event in Collagen IV Mediated Adhesion and Proliferation of Human Ling Tumor Cell Line, Calu-1. Thor.Surgery 2004; 78:450-457.
  8. Wilbur A, O Connor TP, Lu ML, Schneider MC. DNASE1L3 Deficiency in Lupusprone MRL and NZB/W F1 Mice. Clin Exp Immunol 2003; 134:46-52.